Evaluation of the residual solvent content of counterfeit tablets and capsules.
; Canfyn, Michael ; Sacré, P-Y ; Courselle, Patricia ; De Beer, J O.
Canfyn, Michael
Sacré, P-Y
Courselle, Patricia
De Beer, J O.
Citations
Altmetric:
Abstract
A group of counterfeit samples of Viagra and Cialis were screened for their residual solvent content and compared to the content of the genuine products. It was observed that all counterfeit samples had higher residual solvent contents compared to the genuine products. A more diverse range of residual solvents was found as well as higher concentrations. In general these concentrations did not exceed the international imposed maximum limits. Only in a few samples the limits were exceeded. A Projection Pursuit analysis revealed clusters of samples with similar residual solvent content, possibly enabling some future perspectives in forensic research.
Description
Date
2003-12-31
Journal Title
Journal ISSN
Volume Title
Publisher
Chapter title
Publication type
Peer reviewed scientific article
Collections
Research Projects
Organizational Units
Journal Issue
Keywords
Capsules, Carbolines, Counterfeit Drugs, Gas Chromatography-Mass Spectrometry, Guidelines as Topic, Phosphodiesterase 5 Inhibitors, Piperazines, Purines, Sildenafil Citrate, Solvents, Sulfones, Tablets, Tadalafil
