Minimal number of chromatographic test parameters for the characterisation of reversed-phase liquid chromatographic stationary phases
Ivanyi, T. Vander Heyden, Y. Visky, D. Baten, P. de Beer, J.L. Lazar, I. Massart, D.L. Roets, E. Hoogmartens, J.
Ivanyi, T.
Vander Heyden, Y.
Visky, D.
Baten, P.
de Beer, J.L.
Lazar, I.
Massart, D.L.
Roets, E.
Hoogmartens, J.
Citations
Altmetric:
Abstract
This paper focuses on the classification or differentiation of RP-HPLC columns based on measured chromatographic properties. A chemometric study has been conducted on a published data set consisting of 85 RP-HPLC columns and on a data set consisting of 47 self-tested columns. Principal component analysis enables determination of the number of parameters necessary for a rational differentiation. The results show that reducing the number of parameters for such differentiation still allows classification of the columns just as a higher number did. It is shown that three test parameters produce a classification similar to that obtained with five parameters
Description
Date
2002-04-19
Journal Title
Journal ISSN
Volume Title
Publisher
Chapter title
Publication type
Peer reviewed scientific article
Collections
Research Projects
Organizational Units
Journal Issue
Keywords
analysis, article, AS, Belgium, Chromatography,High Pressure Liquid, classification, data, Hydrogen-Ion Concentration, im, instrumentation, IS, journal, methods, Paper, parameters, Principal component, Principal Component Analysis, Print, reducing, Research, Research Support, result, results, SB - IM, Still, study, Test