This report (published in May 2021) is dedicated to the SARS-CoV-2 wastewater national surveillance in Belgium and aims to broadly communicate about the project objective, the epidemiological results available, as well as the framework of the alerting system developed.

The results of SARS-CoV-2 wastewater surveillance can support crisis management and decision-making. They should be considered complementary to the other available surveillance indicators (laboratory-based positive cases, hospitalizations, changes in testing policy, etc.) in the light of the emergence of SARS-CoV-2 variants of concern.
; Although further developments are still ongoing to better define the predictive performance of the SARS-CoV-2 wastewater-based surveillance, it appears as a valuable tool for the follow-up of the epidemiological situation in Belgium.