Emergence of ST131 carrying carbapenemase genes, European Union/European Economic Area, August 2012 to May 2024.
Kohlenberg, Anke Svartström, Olov Apfalter, Petra Hartl, Rainer Bogaerts, Pierre Huang, Te-Din Chudejova, Katerina Malisova, Lucia Eisfeld, Jessica Sandfort, Mirco
Kohlenberg, Anke
Svartström, Olov
Apfalter, Petra
Hartl, Rainer
Bogaerts, Pierre
Huang, Te-Din
Chudejova, Katerina
Malisova, Lucia
Eisfeld, Jessica
Sandfort, Mirco
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Abstract
Analysis of 594 isolates of sequence type (ST)131 and its single locus variants carrying carbapenemase genes from 17 European Union/European Economic Area countries revealed acquisition of 18 carbapenemase variants, mainly in ST131 clades A and C. Most frequent were (n = 230) and (n = 224), detected in 14 and 12 countries, respectively. Isolates carrying have increased rapidly since 2021. The increasing detection of carbapenemase genes in the high-risk lineage ST131 is a public health concern.
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2024-11-01
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Peer reviewed scientific article
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Anti-Bacterial Agents, Bacterial Proteins, beta-Lactamases, Escherichia coli, Escherichia coli Infections, Escherichia coli Proteins, Europe, European Union, Humans, Microbial Sensitivity Tests, Multilocus Sequence Typing