Mycobacterium tuberculosis lacking all mycolic acid cyclopropanation is viable but highly attenuated and hyperinflammatory in mice
Barkan, D. Hedhli, D. Yan, H-G. Huygen, K Glickman, M.S.
Barkan, D.
Hedhli, D.
Yan, H-G.
Huygen, K
Glickman, M.S.
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Abstract
Mycolic acids, the major lipid of the
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Date
2012-07-01
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Peer reviewed scientific article
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Keywords
acid, Acids, Activity, ALL, AS, Cell, Cell Wall, Class, Deficiency, Development, DRUG, effect, effects, Establish, function, Functional, Genetic, immune response, in vivo, INFECTION, IS, IT, M, M.tuberculosis,mycolic acid,cyclopropanatio, mice, Mycobacterium, Mycobacterium tuberculosis, Mycolic Acids, questions, resistance, response, result, results, strain, stress, study, Target, Transferases, Tuberculosis, virulence