A lot of substances in food and feed can interfere with the hormonal system of humans and animals by influencing the synthesis, metabolism or transport of hormones; or by interacting directly with the hormone receptor (as an agonist or antagonist). Over the past decades there has been a growing concern about the exposure of animals and humans to these endocrine disrupting chemicals (EDCs). EDCs can be chemicals of synthetic (pesticides, industrial chemicals,bisphenols,...) or natural origin (mycotoxins, fytoestrogens,…)(Diamanti-Kandarakis et al., 2009).